What is saffron?
Saffron is the stigma of the Crocus sativus, the most antioxidant-rich plant known and the most expensive spice and herb. For more than 3,000 years, saffron has also been treasured as a treatment for a wide assortment of maladies. Growing evidence of clinical and preclinical studies in recent years has further revealed that saffron and its main active constituents exert potential neuroprotective, nootropic, anti-convulsant, anti-depressive, anxiolytic, antioxidant, anti-inflammatory, hypolipidemic, anti-atherogenic, anti-hypertensive, and even anti-cancer effects.
Crocin is the main active constituent identified responsible for the amazing health benefits of saffron. It is a type of pigment molecule known as a carotenoid and gives saffron its royal red color. Unlike other carotenoids such as lycopene, β-carotene, lutein, zeaxanthin, etc. which are fat-soluble, crocin is unique as it is the only water-soluble carotenoid in the nature and is not present in ordinary fruits or vegetables. Found as one of the most potent antioxidants and anti-inflammatory agent with multi-target effects to protect cells from chemical and radical damages and to improve memory and cognition, crocin is gradually recognized as the best natural ingredient for our health.
Is crocin a over-the-counter medicine or pain killer?
No. Crocin described here is the chemical name of a unique water-soluble carotenoid found in saffron which may have pain suppressive effect. However, the popular over-the-counter medicine made with acetaminophen has a few different trade names including Tylenol® in the USA and Crocin® in some countries such as India. So this crocin is not acetaminophen.
Why is crocin more effective than saffron?
Crocin is the most important active constituent that provides the health effects of saffron. Quality of saffron, like any plant materials, varies significantly in amount of crocin which is affected by region, weather, drying process, and other factors. Additionally, saffron has been documented to be subjected to adulteration since Middle Age. Therefore, purified natural crocin offers potent and consistent biological effects that saffron doesn't.
Why is crocin superior to other carotenoids?
Crocin is the only water-soluble carotenoid in nature and readily absorbed by our body, making it more stable and effectively utilized than the other (fat soluble) carotenoids. Published studies demonstrated crocin is more effective and multi-targeting for our health. Crocin is not present in common fruits and vegetable. It is especially beneficial as a component in the supplement for good health. Other carotenoids are available from various food sources, including carrot, tomato, corn, egg yolk, orange fruits, and green vegetables.
Are there research studies about crocin health beneficial effects?
Crocin is a new and truly amazing ingredient. In the last 20-30 years, significant numbers of studies have been published about crocin’s multi-target health benefits. A dozen of human RCT studies have reported that crocin provided significant improvements in patients with Type II diabetes, coronary artery disease, acute ischemic stroke, multiple sclerosis, osteoarthritis, diabetic maculopathy, etc. Search in the public domain will reveal abundant information about the effects of crocin on many aspects of health conditions.
What is the difference of saffron and saffron extract?
Common sense tells saffron extract would be better than saffron, which is true in most published studies. However, “Satiereal” or “Saffron Extract” used in supplements in the USA is a saffron ingredient added with 5-6 times by weight of cellulose (additive) in the extraction processing (Nutrition Research. 2010, 30: 305–313). “Satiereal” or “Saffron Extract” contains only about 16% of saffron. So “Satiereal” or “Saffron Extract” supplement products on the market in the USA is not better than saffron. The study suggested 176.5mg per day of Satiereal (Saffron extract) reduce food craving and increase satiety for weight management is also refuted by two recent studies (J Diet Suppl. 2018, 15(6): 965-976 & J Clin Pharm Ther. 2020, 45(1): 134-143).
What is Crocin Rich® ?
Crocin Rich® is the first and only high purity natural crocin reviewed and granted NO OBJECTION by FDA in the USA. It is produced with the most advanced purification techniques under strict quality control. Crocin identity and purity of Crocin Rich® are confirmed and determined by HPLC, LCMS, and QNMR. Crocin Rich® offers optima crocin effects for its products.
Are CROCIN RICH products safe?
CROCIN RICH products are designed and formulated with all the active ingredients extracted and purified only from edible natural sources. Each and every ingredient in the product has good safety profile and use history. Certificate of Free Sale from FDA was issued for CROCIN RICH products. As dietary supplements, it is always recommended to consult with your physician or other qualified health professional before taking a new course of supplementation.
How were CROCIN RICH products developed?
CROCIN RICH products were developed through years of research and development by scientists in the USA, who are experts of natural products/ingredients and have in-depth knowledge of saffron and crocin. They are determined to bring safe, the best, and most beneficial supplement products from nature to the market.
What are the side effects of CROCIN RICH products?
CROCIN RICH products are comprised of the most effective ingredients extracted and purified only from edible natural sources. No adverse effects have been reported by users of CROCIN RICH products.
Are there any cautions regarding the use of CROCIN RICH products?
As is the case with all dietary supplements, you should consult with your doctor or other qualified health professionals regarding the treatment of medical conditions before using this product.
What ensures the potency and consistency of CROCIN RICH products?
CROCIN RICH products are manufactured in the USA according to good manufacturing practice (GMP) with the best quality ingredients. For example, the identity and high purity of the key ingredient, Crocin Rich® is measured and determined by the most advanced analytical technologies, including HPLC (High-performance liquid chromatography), LCMS (Liquid chromatography-mass spectrometry), and qNMR (quantitative NMR) techniques. This ensures consistency of dosage and potency of the product.
What is the difference between the CROCIN RICH products?
Each tablet of CROCIN RICH provides a dose of crocin (equivalent to 90 mg of top-grade saffron) plus lutein and zeaxanthin. Each tablet of CROCIN RICH II provides a higher dose of crocin (equivalent to 275mg top grade saffron), 3X potency of CROCIN RICH.
CROCIN RICH plus is a patented product (US9211298). Each tablet provides a higher dose of crocin (equivalent to 300mg top grade saffron) plus six other potent natural antioxidants and enhancers for best effects. More than 3X potency of CROCIN RICH.
CROCIN RICH products are packaged in a convenient two-month supply (60 coated tablets per bottle).
While all CROCIN RICH products enhance our health in a range of areas, products at higher dosages prove to be more effective. These products provide meaningful effects for your natural well-being of body and mind*. Particularly, CROCIN RICH plus offers the highest usage of crocin in our patented formulation for the best results.
Why do CROCIN RICH products cost more than other saffron-based supplements?
Saffron is a very expensive product to cultivate and process. It takes approximately 200 flowers to yield just 1,000 mg (0.035 oz.) of dry saffron threads and costs $2,000 to $5,000 a pound on the market. Saffron has been a subject of high frequent adulteration since Middle-Age. Quality of saffron and content of crocin in saffron vary significantly.
“Saffron Extract” products on the US market are diluted in content and not comparable to saffron itself. “Satiereal”, a "Saffron Extract" provides 3-4 times LESS saffron content because it was diluted by adding 6 times of fiber in its extraction process (Nutrition Research 2010, 30: 305–313). In fact, a third party study reported by scientists at Hofstra University found a dietary supplement containing 178 mg satiereal, 100mg naringin, and 2,000 IU vitamin D3 did not have any detectable beneficial effects on body-weight management (Journal of Dietary Supplements 2018,15(6): 965-976). Similarly produced "Saffron Extract” only gives a misleading “better than” saffron impression. Shoppers should compare saffron with “Saffron Extract” products and ask: Is it possible that product of “Saffron Extract” can cost far less than saffron itself.
CROCIN RICH products provide a high dose of the active component, crocin, for meaningful benefits. Crocin Rich® has been carefully reviewed and granted NO OBJECTION by FDA. Crocin identity and purity are determined and ensured by the most advanced analytical technologies, including HPLC (High-performance liquid chromatography), LCMS (Liquid chromatography-mass spectrometry), and qNMR (quantitative NMR) techniques. CROCIN RICH products received Certificate of Free Sale from FDA.
How do I store CROCIN RICH? Does it need to be refrigerated?
CROCIN RICH products are specially offered in coated tablet form, best for potency and stability. It can be stored at room temperature, preferably under dry and cool conditions.