Age-related Neurodegenerative Disease? What Is It?
Aging is a progressive process and may lead to some neurodegenerative diseases. Many people think it’s natural to forget things, have poor eyesight, wake up frequently in the night, and shaking hands, etc. when they get old. These are likely symptoms of age-related diseases, such as Alzheimer’s disease, macular degeneration, Parkinson’s disease. But these neurodegenerative diseases are not part of the normal aging. Without prevention or treatment, such conditions are progressively worsening and irreversible. Most people don’t pay attention or notice these age-related neurodegenerative diseases until they get to the mild-to-moderate stage. As one of the major age-related neurodegenerative diseases, Alzheimer’s disease (AD) affects memory, language, problem-solving and other cognitive skills serious enough to affect a person’s ability to perform everyday activities. AD also inflicts significant financial, social and emotional burden to families and society.
Currently, there is no cure for Alzheimer’s disease or a way to stop or slow its progression. Research in the past many years has gained a significant understanding of its causes. AD is caused by not a single but multiple risk factors include age, heredity, diabetes, smoking, heart disease, brain injury, hypertension, hyperlipidemia, depression, infection, oxidative stress, inflammation, poor sleep, amyloid plaques in the brain, etc. The approach taken by pharmaceutical companies targeting one of the hallmark biomarkers, such as amyloid-β (Aβ), or other biomarkers has failed so far. A growing consensus among scientists is as Maria C. Carrillo, Ph.D., Alzheimer’s Association chief science officer, said on July 27, 2016: “In Alzheimer’s, the most likely scenario for successful future treatment is addressing the disease from multiple angles.”
Nature is a source of a multi-target solution for the prevention and treatment of Alzheimer’s disease. For thousands of years, traditional herbal medicines have been used to delay or treat various diseases, including Alzheimer’s and dementia. Traditional medicines usually contain multiple herbal components and act on many bio-targets or regulate different layers of body systems.
Therefore, a multi-component and multi-targeting approach can be developed from dietary or edible plant sources as a safe and effective natural alternative for the prevention and treatment of AD.